A fast, effective and low cost sample preparation method based on miniaturized matrix solid-phase dispersion (micro-MSPD) combined with gas chromatography coupled to tandem triple-quadrupole-mass spectrometry (GC–MS/MS) has been developed for the determination of six phthalate diesters (DMP, DEP, DBP, BzBP, DEHP and DnOP) in mussel samples. The six target compounds have been included in the list of priority pollutants by United States Environmental Protection Agency. The extraction step was optimized on real spiked mussel coming from Galician Rías by means of a factorial design.

This work studies the chlorination and monochloramination reaction kinetics of two phenazone-type drugs (phenazone – Phe and propyphenazone – PrPhe) and three metabolites of phenazone-type drugs (4-formylaminoantipyrine – FAA, 4-aminoantipyrine - AA and 4-acetoamidoantipyrine - AAA). Kinetics were faster with chlorine (apparent second-order constants between 100 and 66,500 times higher) than with monochloramine. For FAA and AAA, no significant reaction was observed during monochloramination.

OCs (organochlorine compounds), such as PCBs (polychlorinated biphenyls) and OCPs (organochlorine pesticides), and PAHs (polycyclic aromatic hydrocarbons) were determined in wild and raft mussels collected in several stations from Ría de Vigo during the period 2010–2019. The concentration levels of ΣPCBs ΣDDs (sum of pp’-DDE and pp’-DDD metabolites) and ΣPAHs ranged from 22.1, 2.63 and 7.55 ng g−1 to 58.0, 6.89 and 25.2 ng g−1 dry weight, respectively.